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Immortalized human myoblasts as an innovative cellular tool

For years, research into muscle dystrophies has been limited due to the fact that the animal-derived dystrophic cellular models, which are required to carry out the research, have low proliferative...

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Targeting skeletal muscle to treat SBMA

Two recent reports by Cortes et al. and Lieberman et al. reveal a novel role of skeletal muscle on SBMA pathology and opens new avenues for alternative therapies against motor neuron disorders....

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Tackling ischemia to treat DMD

In a recent publication Nelson et al proposed to use PDE5 inhibitors to treat DMD.   Duchenne Muscular Dystrophy (DMD) is a fatal progressive disease that affects about one in 3500 boys. DMD is caused...

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